This is a core function for ABC inference using demografr. It generates simulation replicates and computes summary statistic for the next step of an inference procedure, which is the ABC estimation itself.

simulate_abc(
  model,
  priors,
  functions,
  observed,
  iterations,
  sequence_length,
  recombination_rate,
  mutation_rate = 0,
  data = NULL,
  format = c("ts", "files"),
  file = NULL,
  packages = NULL,
  attempts = 1000,
  engine = NULL,
  model_args = NULL,
  engine_args = NULL
)

Arguments

model

Either a slendr model generating function (in which case engine must be either "msprime" or "slim", i.e. one of the two of slendr's simulation back ends), or a path to a custom user-defined SLiM or msprime script (in which case engine must be "custom").

priors

A list of prior distributions to use for sampling of model parameters

functions

A named list of summary statistic functions to apply on simulated tree sequences

observed

A named list of observed summary statistics

iterations

How many simulation replicates to run?

sequence_length

Amount of sequence to simulate using slendr (in numbers of basepairs)

recombination_rate

Recombination rate to use for the simulation

mutation_rate

Mutation rate to use for the simulation

data

A named list of data-generating functions. The names then represent all possible arguments of simulated summary statistic functions.

format

In which format will the model generate results to be used for computing simulated summary statistics?

file

If not NULL, a path where to save the data frame with simulated grid results

packages

A character vector with package names used by user-defined summary statistic functions. Only relevant when parallelization is set up using future::plan() to make sure that the parallelized tree-sequence summary statistic functions have all of their packages available.

attempts

Maximum number of attempts to generate prior values for a valid demographic model (default is 1000)

engine

Which simulation engine to use? Values "msprime" and "slim" will use one of the built-in slendr simulation back ends. Which engine will be used is determined by the nature of the model. If engine = NULL, then spatial slendr models will by default use the "slim" back end, non-spatial models will use the "msprime" back end, and custom user-defined model scripts will use the "custom" engine. Setting this argument explicitly will change the back ends (where appropriate). Setting this argument for custom simulation script has no effect.

model_args

Optional (non-prior) arguments for the slendr model generating function. Setting this argument for custom simulation script has no effect.

engine_args

Optional arguments for the slendr simulation back end. Setting this argument for custom simulation script has no effect.

Value

A list object of the class demografr_abc_sims containing the results of ABC simulations, sampled parameters, priors, and tree-sequence summary statistics